Hull FC chairman Andrew Thirkell said he was “delighted” to be part of the occasion.
“We know our supporters enjoy making special occasions of away fixtures. Dublin provides the perfect destination for what we hope will become a fantastic rugby league weekend,” he said.
“We are pleased to be working alongside St Helens on our fixture and collectively with Wigan Warriors and Warrington Wolves to deliver something that we believe will be a tremendous spectacle both on and off the field.”
The game will be played at Laya Arena, the refurbished 20,000-capacity home of Leinster rugby union.
McManus added: “It’s going to be fantastic for rugby league, we will showcase our game to the Irish who will be open to this sport and will love it. It’s going to be a great weekend for us all.”