Wiegman said she “can’t control” what Earps says or feels about her decisions but the England coach emphasised she made the decisions to give the side the best chance of success.
England take on China at Wembley Stadium on 29 November before hosting Ghana at St Mary’s Stadium on 2 December.
The media conference to announce her squad was dominated by questions about Earps and Wiegman joked it would be “nice to talk about football”.
The return of Manchester City forward Lauren Hemp and midfielder Grace Clinton are the headline stories in Wiegman’s 25-player squad for the friendly matches.
But former Netherlands coach Wiegman accepted that dealing with adversity is part of her high-profile role.
“Of course you hope that things are always positive but that’s not how things work in football when you’re so visible,” she said.
“It’s just the situation and you’re trying to deal with it in the best positive way, solve whatever needs to be solved, and move forward.
“I make decisions on what I think is the best for the team to compete in the next camp or the next tournament – and I make decisions to win.”
Wiegman was also asked if she was disappointed that Earps said her affinity to the Lionesses manager was “destroyed” and her “trust and respect was evaporating”.
“I don’t think I can change that. What I just try to be is as honest as possible and have a very good working relationship, which is what I think we had,” she added.
“I can’t control other things. I just stick with what I want to do, how I want to do it and try to be as clear and honest as possible to make decisions to win.
“I always keep conversations private. I share things here [in the media] but when I have individual conversations I keep that private as that builds trust.
“If I do that then players will come to me and have conversations with me. That’s my approach. We create an environment where we want people to be themselves.”
Chelsea goalkeeper Hampton is not in the squad for the final two England matches of the year after picking up a thigh injury.
The 24-year-old won the Yashin Trophy for best goalkeeper at this year’s Ballon d’Or awards, and was one of the standout performers at Euro 2025.
Wiegman confirmed she had spoken with Hampton following Earps’ book release but did not go into details on their conversations.
“I spoke to Hannah. I speak to players in between camps anyway. Unfortunately, she is injured now. But I did speak to her, yes,” added Wiegman.
“What the content of that conversation was, as always, I’ll keep private.”