Wilkinson, who represented Canada at four World Cups, says anyone who does not enjoy women’s football should simply stay away from the sport.
“I think there’s this piece of women versus men and I think we’re all here because of sport,” she added.
“That’s just what we need to come back to, that if you don’t enjoy watching women’s football, please don’t watch it.
“If you’re a fan of Welsh football, please cheer on all levels, all genders, just to make sure we’re giving our young people every opportunity to achieve their own ambitions.”
Wrexham have issued a statement warning that any supporter found to be involved in the online abuse will be banned by the club.
“We are aware of sexist and misogynistic comments shared online following the [Cardiff] match,” they said.
“We stand unequivocally with our players and staff. As a club, we will always support and protect them, and we will continue to promote an environment that is inclusive, welcoming and respectful for all.
“Wrexham AFC will not tolerate discrimination of any kind. Those who hold or express such views are not part of our community. If supporters are identified, then we will ban individuals from all Wrexham AFC sites.”