Anticipation was high among the Australian fans arriving at Rod Laver Arena that De Minaur could cause a shock – particularly given the uncertainty about Sinner’s condition.
De Minaur came into the match with a terrible record against his opponent, losing all nine of their previous matches and winning only one set in the process.
The 25-year-old was looking to end that unwanted statistic and become the first home player since 2005 to reach the men’s singles semi-finals.
But what was expected to be a raucous atmosphere in the night-session match failed to materialise.
It was testament to Sinner’s assured display that he quickly quietened De Minaur and largely silenced the majority of the 15,000 fans.
Sinner struck the ball sweetly and consistently to outlast De Minaur in the rallies.
“I feel like today I was feeling everything. When you break early in each set it is a little bit easier,” added Sinner.
“Yesterday was a very easy day, I played just half an hour or 40 minutes with my coaches, they gave me rhythm.
“I felt ready for today, when you play night session you try to sleep as long as you can and eat healthy.”