Holders Hull Kingston Rovers will play Warrington Wolves in the semi-finals of the 2026 Challenge Cup, while St Helens will face bitter rivals Wigan Warriors.
Holders Rovers won the trophy by beating Wolves in last year’s final.
The semi-final draw was held at half-time during a quarter-final thriller between Wigan and Wakefield, which the Warriors won in dramatic fashion.
The ties will be played between 9 and 10 May at neutral venues, which have yet to be decided.