Time is running out for the Red Devils to secure Champions League football for next season with tonight’s clash against the Blues a must-win fixture.
Ralf Rangnick’s United have lost three of their last four in the Premier League and sit six points behind Arsenal having played a game more ahead of this Thursday night match-up.
In third, Chelsea enjoy a big advantage over the chasing pack and will go ten points clear of fifth-placed Tottenham with five games to go, if they can secure a victory in Manchester.
Christian Pulisic delivered the latest of wins for the capital club last time out as they downed West Ham, their first win at home in over a month.
Chelsea have found matters easier going on the road however and have not lost to United in their last four meetings.
With kick-off at 7.45pm BST, follow Standard Sport’s live blog for all the latest updates including expert analysis from James Robson at the ground…
The last three meetings have ended all square.
Manchester United wins: 81
Chelsea wins: 55
Evening Standard score prediction
Two sides out of form, United’s sheer amount of defensive problems could let Chelsea in to pile on more misery.
Chelsea to win 2-1.
Predicted Chelsea XI: Mendy; Chalobah, Silva, Rudiger; James, Kante, Loftus-Cheek, Alonso; Mount, Havertz, Werner.
Predicted Man United XI: De Gea; Dalot, Varane, Lindelof, Telles; McTominay, Matic; Elanga, Fernandes, Rashford; Ronaldo.
For Chelsea, Mateo Kovacic (ligament) will sit this one out as well as Ross Barkley (illness), Ben Chilwell (knee) and Callum Hudson-Odoi (back).
Reece James remains a doubt but trained on Tuesday as he nears a return from a hamstring issue, although Tuchel confirmed ahead of the game that Andreas Christensen is more likely to be unavailable. Antonio Rudiger could also return.
Early team news
United head into this game with a lengthy injury list.
Paul Pogba, Edinson Cavani, Luke Shaw and Fred will all continue to be out of action, Harry Maguire is missing due to a knee injury whereas Jadon Sancho has come down with tonisillitis, ruling him out.
How to watch
TV channel: In the UK, Manchester United vs Chelsea will be broadcast live on Sky Sports Main Event, Sky Sports Premier League and Sky Sports Ultra HD. Coverage begins at 7pm.
Live stream: Sky Sports subscribers will also be able to watch the game live online via the Sky Go app.
And welcome to Standard Sport’s coverage of Manchester United versus Chelsea.
What was once the game of the season is now a mere footnote in a midweek of European action, but still could have huge consequences in the race for the top four.
Kick-off is at 7.45pm BST and we will bring you all the build-up, including team news in just over an hour.