Lancashire begin their Division Two campaign against Middlesex on 4 April at Lord’s, where Anderson played his final Test against West Indies.
Despite since working with England as a bowling consultant, Anderson expressed a desire to continue playing.
Anderson will be part of England’s staff for the Champions Trophy in February and March but no deal has been agreed for this summer. It is understood Ben Stokes’ side are keen for him to return.
Anderson said it is not yet clear what resuming his playing career will mean for his role with England this summer but added he will prioritise appearing for Lancashire if selected.
“I don’t think it would be fair on Lancashire if I just dipped in and out,” he said.
“It’s only fair that I give it a good crack and that’ll take precedence over anything else during the summer.”
Anderson retired from internationals after England opted to look to the future with their bowling attack, finishing with 704 Test wickets – the most by a pace bowler and third most overall.
He has taken 1,126 wickets in 298 first-class matches, with 376 of those wickets coming in 95 matches for Lancashire since his debut in 2002.
“The one thing I’ve known for many months is that I wanted to play cricket,” said Anderson, who turns 43 in July.
“It was just trying to find what sort of cricket I wanted to play and after a few chats with Lancashire and their plans for the year it just felt like a nice thing to do.”
Anderson could play his first T20 match in nearly 11 years when Lancashire’s Blast campaign begins on 29 May.
He has not played any white-ball cricket since 2019 but has recently tried to enter franchise cricket, going unsold in the Indian Premier League auction in November.