Cricket Ireland said “full support” would be given to Maguire, who was not selected for Sunday’s match despite being permitted to continue bowling in international cricket until the test results are known.
Ireland struggled to contain the India batters with captain Smriti Mandhana (73) and Pratika Rawal (67) putting on 156 for the opening partnership.
Rodrigues and Deol then combined for a 183-run stand as India posted a daunting target.
The tourists lost skipper Gaby Lewis for 12 before her opening partner Sarah Forbes (38) and Coulter Reilly took Ireland to 87-1.
After Forbes fell, Coulter Reilly and Laura Delany (37) put on 83 for the fourth wicket, but Ireland were well behind the required run-rate.
They could only manage 254-7 from their 50 overs with Deepti Sharma taking 3-37, while Orla Prendergast was the pick of the Irish bowlers with 2-75.
The sides will meet at the Niranjan Shah Stadium again on Wednesday for the third and final ODI.
