Stones limped off against Real Madrid in Tuesday’s Champions League thriller and it is currently touch and go as to whether or not he will be able to feature in the return leg this coming Wednesday.
Walker, meanwhile, is still suffering from an ankle problem.
On Friday, Guardiola said of the defender: “He’s injured – unfortunately for all of us and him especially – but I don’t pay attention. He has to work to come back as soon as possible. I am focused on the rest of the players.”
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With the semi-final away in Spain to come in midweek, Bernardo Silva and Kevin De Bruyne drop to the bench and are seemingly being saved for that huge match.
Ilkay Gundogan, Nathan Ake, Raheem Sterling and Jack Grealish all come into the side, while Joao Cancelo returns following his suspension in Europe.
This is a fine balancing act for City. Any slip-up in the league could easily hand Liverpool the title but players need resting, with the Champions League naturally a key focus.
Starting XI: Ederson, Cancelo, Dias, Laporte, Ake, Rodri, Gundogan, Grealish, Jesus, Foden, Sterling
Subs: Steffen, Zinchenko, De Bruyne, Bernardo, Fernandinho, Mahrez, Egan-Riley, Mbete, McAtee